Showing posts with label Cancer. Show all posts
Showing posts with label Cancer. Show all posts

Saturday, November 7, 2009

Hi-Tech Health Care


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With a speakers list ranging from Deepak Chopra to Steve Wozniak, to Goldie Hawn and David Blaine, the TEDMED 2009 Conference brought together some of the worlds greatest minds to discuss the future of health care technology.


The most interesting innovations didn't come from Hollywood, of course, but from exciting new companies converting research successes into technological marvels.

On the cancer front, the Pink Army Cooperative seeks to destroy breast cancer cells using synthetic, tumour-killing viruses. The viruses will be initially tested on cells taken from a patients' own tumour before being introduced into the body.

Another company, HopeLab, has designed a video game that helps kids respond better to cancer treatments, called Re-Mission. The user plays the role of a nanobot that destroys malignant cells with drugs and radiation.

Wi-Fi gadgets also had a big presence at the conference. The Corventis PiiX monitor sticks to your chest, looks no bigger than a cell phone, but can measure and transmit about a dozen different vital signs at a time. Another device, Zeo, is an alarm clock that records your brain waves as you sleep.

Finally, and most impressively, tissue engineering is moving ahead leaps and bounds. A company called Organogenesis is using sheets of lab-grown tissue to heal difficult wounds like diabetic ulcers. The grafts, shown above, consist of cells grown on a flexible collagen support matrix.

Whole organs are not far off, especially considering the announcement of a potential X-Prize competition dedicated to this end. Perhaps some custom-made hearts and brains are in order for US legislators?

~Rheanna Sand

Thursday, October 29, 2009

The Secret to Cancer Immunity

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... Is the naked mole rat.




Not the most impressive-looking rodent in the animal kingdom, but it's certainly one of the most interesting.

Living underground in subterranean tunnels that can stretch up to three miles, the mole rat is one of the only mammals to live in a eusocial society with a fertile queen and sterile workers, very similar to in an ant colony.

It's long been known that these creatures have a variety of interesting adaptations, including the ability to live with hardly any oxygen or food, and to eat their own excrement. But they're also the longest living rodents on earth, with lifespans of up to 28 years, and – here's the big one – are essentially immune to cancer.

And researchers at the University of Rochester have discovered why. It turns out that while humans have only one contact-inhibition system for cancer based on a gene called p27, mole rats have two. The second system uses a gene called p16-ink4a to prevent cells from overgrowing at an earlier stage than p27, heading off potential cancers before they have a chance to start.

This finding is a big breakthrough for cancer research, particularly because humans also have the p16-ink4a gene, though it doesn't seem to play the same role in our cells as it does for the mole rats.

But more importantly from the naked mole rat's point of view, it ensures that these magnificent creatures will go down in history for more than just the whole "eating-their-own-faeces" thing.

So, you're welcome, mole rats.

- Brit Trogen